Seqens’ technical and manufacturing teams have successfully completed countless cGMP medical-grade polymer synthesis projects, including:

  • Drug delivery technology
  • Excipients
  • Medical devices (510k)
  • Medical-grade coatings
  • Therapeutics

These projects begin in our laboratories, to enable our teams to improve many polymerization processes and to adopt the latest analytical techniques supporting their development. Seqens has the capacity to produce our cGMP polymers in quantities ranging from kilos to tons.

PEKK polymers

  • PEKK (Poly-Ether-Ketone-Ketone) polymers, which are useful for long-term implantable human devices with a life cycle of several years. These polymers are widely used as orthopedics, neurological, dental, spinal and cardiovascular implants as well as in PEKK-based 3D-printed bones.

Catalog on demande

Seqens alsooffers development of other cGMP medical grade polymers such as hydroxybutyrate, (poly)ester, acrylate and methacrylate copolymers.

Our locations

Address Route de Lassay
61410 Couterne
Business Line Lubbricant Additives, Fine Chemicals
Phone +33 2 33 37 50 20
Market Specialty Ingredients
Mail info.AS@seqens.com
More information

Surface: 120, 000 m²

Capabilities: 190 m³ of ISO 9001 reactors and kilo-lab

Flagship technologies: Most standard organic synthesis reactions (large volumes)

Certifications: ISO 9001

Address Expansia, Route d'Avignon
30390 Aramon
Business Line Contract Manufacturing
Phone +33 4 66 57 01 01
Market Pharmaceutical
Mail info.cdmo@seqens.com
More information

Capabilities: 

  • 100 m³ of GMP reactors
  • 50 L – 10 000 L vessels

Flagship technologies: 

  • Organometallic chemistry
  • Large-scale hydrogenation
  • Diborane chemistry
  • Ethylene oxide reactions
  • Biocatalysis platform
  • Polymer production (PLGA)
  • Enzymatic synthesis Skraup reactions
Address 9 Opportunity Way
MA 01950 Newburyport
Business Line Custom Early Phase Pharmaceutical
Phone (978) 462 5555
Market Pharmaceutical
Mail derek.richards@seqens.com
More information

Surface: 5, 600 m²

Lab surface: 460 m²

Capabilities:

  • Process Research – Custom synthesis & synthetic route evlaution from g – kg for API’s or intermediates
  • Process Development – Custom synthesis from kg – metric tons
  • cGMP Small Molecule API Manufacturing (Phase 1, Phase 2, Phase 3, Commerical)
  • cGMP Medical Grade Polymers, Analytical Method Development

Flagship technologies: 

  • Controlled Substances
  • Cryogenic Chemistry -90°C
  • Lyophilization, Small/Large Scale Chromatography
  • Tangential Flow Filtration

Last inspection: July 2018 FDA Inspection

Address ZI de Limay 2, 8 Rue de Rouen
78440 Porcheville
Phone +33 1 34 79 57 00
Market Pharmaceutical, Specialty Ingredients & Cosmetics
Mail ContactSeqensPCV@seqens.com
More information

Surface: 40 000 m²

 

Lab surface: 2 000 m²

 

Capabilities:

  • 4 kilo-labs
  • 2 cGMP pilot plants with 11 multipurpose reactors from 100 L to 2 800 L (total capacity of 12 m³)
  • Temperature range: -15/+150°C  (hastelloy reactor: -80/+200°C)
  • 3 finishing rooms (agitated filter dryers, filters, dryers, milling and sieving equipments)

Flagship technologies:

  • Crystallization expertise and technologiesd(salt, co-crystal and polymorph screenings, process development)
  • Process Safety expertise and tecnologies
  • Flow chemistry for fine chemicals
  • Potent API process development
  • Genotoxic Impurities
  • Issue Management
  • Generic A.P.I Solid state expertis

Last inspection: ANSM  October 2018

Certification: cGMP

 

Number of scientists: 110

 

Other: Ecosystem Pharma with integrated services

 
Address 88 Jackson Road, Building 649
MA 01434 Devens
Business Line R&D center
Phone (978) 772 2111
Market Pharmaceutical
Mail Accueil@seqens.com
More information

Lab surface: 1 000 m²

Capabilities:

  • Controlled substances (Schedule II-V)
  • 5 Kilo-Labs

Number of scientists: 30