Each site in Seqens’ global manufacturing network is committed to development and manufacturing excellence

France

  • Aramon: cGMP production of clinical stage APIs and intermediates from grams to multi-ton commercial scale
  • Bourgoin: Pre-GMP production of regulatory starting material from kilograms to multi-ton commercial scale
  • Couterne: Pre-GMP production of regulatory starting material from kilograms to multi-ton commercial scale
  • Limay: cGMP production of large volume APIs and intermediaries from grams to multi-ton commercial scale
  • Nimes: Biocatalysis and custom enzymes (Proteus)
  • Porcheville: R&D and pilot units for contract small molecule API development
  • Villeneuve-la-Garenne: cGMP production of potent molecules from grams to multi-ton commercial scale


Finland

  • Turku: cGMP production of proprietary APIs from grams to multi-ton commercial scale

Germany

  • Lahr: cGMP production of APIs and pharmachemicals from grams to multi-ton commercial scale and pre-GMP production of regulatory starting material from kilograms to multi-ton commercial scale

United States

  • Devens: R&D and pilot units for contract small molecule API development; production of controlled substances (Schedule II-V)
  • Newburyport: cGMP production of APIs and pharmachemicals from grams to multi-ton commercial scale

Our locations

Address Route de Lassay
61410 Couterne
Business Line Lubbricant Additives, Fine Chemicals
Phone +33 2 33 37 50 20
Market Specialty Ingredients
Mail info.AS@seqens.com
More information

Surface: 120, 000 m²

Capabilities: 190 m³ of ISO 9001 reactors and kilo-lab

Flagship technologies: Most standard organic synthesis reactions (large volumes)

Certifications: ISO 9001

Address Raiffeisenstraße 4
77933 Lahr
Business Line Custom Manufacturing, APIs & Intermediates
Phone 49 7821 585 0
Market Pharmaceutical
Mail info-lahr@seqens.com
More information

Surface: 48 000 m²

 

Lab surface: 700 m²

 

Capabilities:

  • Total reactor capacity: 92 m³
  • Reaction vessels: 1 to 6 300 L; temperature  -80°C to +250 °C
  • Multi-purpose state of the art cGMP facilty: 4 independent, vertical integrated production trains 800 L train, 2 x 3 000 L trains plus 1 x 3 000 L low temperature hydrogenation reactor and 6 000 L train
  • Classic two-floor layout Facility: 20 vessels with capacity between 800 and 6 000 L (glaslined and SS)
  • Autoclaves (operational range up to 100 bar)
  • Kilo-Lab: 3 reactors: 25 / 100 / 250 L

Flagship technologies:

  • Hydrogenation
  • Reductive amination
  • Organometallic reactions
  • Protected AADs (Aminoacid derivatives)
  • Carbonylation & Hydroformylation
  • Pressure aminolysis, other reactions under pressure
  • Cryogenic chemistry
  • Enantiopure synthesis
  • Cyanation high volumes (NaCN) C-C coupling
  • Reductions
  • Halogenation

Last inspections:

  • FDA 2018
  • German Pharma Authority 2018

Certifications:

  • GMP
  • ISO 9001
  • ISO 50001

Number of scientists: 25

 
Address 19 Route de Meulan
78520 Limay
Business Line Contract Manufacturing & Proprietary APIs
Phone +33 1 34 78 87 87
Market Pharmaceutical
Mail info.cdmo@seqens.com
More information

Capabilities: 

  • 70 m³ of GMP reactors
  • 100 L – 8 000 L vessels

Flagship technologies: 

  • Optical resolution
  • Enzymatic hydrolysis
  • Enantioselective reduction
  • Low-temperature reactions (-80 °C)
  • Specific reduction
  • Hydrogenation (40 bar)
  • Organomagnesium compounds
  • Thin-layer distillation
Address Expansia, Route d'Avignon
30390 Aramon
Business Line Contract Manufacturing
Phone +33 4 66 57 01 01
Market Pharmaceutical
Mail info.cdmo@seqens.com
More information

Capabilities: 

  • 100 m³ of GMP reactors
  • 50 L – 10 000 L vessels

Flagship technologies: 

  • Organometallic chemistry
  • Large-scale hydrogenation
  • Diborane chemistry
  • Ethylene oxide reactions
  • Biocatalysis platform
  • Polymer production (PLGA)
  • Enzymatic synthesis Skraup reactions
Address 15 Avenue des Frères Lumière
38300 Bourgoin-Jallieu
Business Line Contract Manufacturing & Fine Chemicals
Phone +33 4 74 93 63 33
Market Pharmaceutical
Mail Acceuil.bourgoin@seqens.com
More information

Flagship technologies: Distillation

Address 35 Avenue Jean Jaurès
92390 Villeneuve-la-Garenne
Business Line Contract Manufacturing & Proprietary APIs
Phone +33 1 34 78 87 87
Market Pharmaceutical
Mail info.cdmo@seqens.com
More information

Capabilities: 

  • 70 m³ of GMP reactors
  • 100 L – 8 000 L vessels

Flagship technologies: 

  • Optical resolution
  • Enzymatic hydrolysis
  • Enantioselective reduction
  • Low-temperature reactions (-80 °C)
  • Specific reduction
  • Hydrogenation (40 bar)
  • Organomagnesium compounds
  • Thin-layer distillation
Address Messukentänkatu 8
20210 Turku
Business Line Contract Manufacturing & Proprietary APIs
Phone +358 2 330 5542
Market Pharmaceutical
Mail info@pcasfinland.fi
More information

Surface: 11 678 m²

Lab surface: 695 m²

Capabilities: 

  • 4 separate modules
  • 72 m³ reactor capacity-
  • 250 L – 6300 L vessels

Flagship technologies:

  • Biphosphonate chemistry
  • Hydrogenation (20 bar)
  • Chlorination
  • Cyanation (NaCN) in separate installations
  • Reduction with complex hydrids
  • Biocatalysis
  • Manufacturing of parenteral/injectable APIs
  • Separate production modules and final processing facilities
 

Last inspections:

  • FDA 2017
  • PMDA 2018
  • FIMEA 2018

Number of scientists: 16

Address 9 Opportunity Way
MA 01950 Newburyport
Business Line Custom Early Phase Pharmaceutical
Phone (978) 462 5555
Market Pharmaceutical
Mail derek.richards@seqens.com
More information

Surface: 5, 600 m²

Lab surface: 460 m²

Capabilities:

  • Process Research – Custom synthesis & synthetic route evlaution from g – kg for API’s or intermediates
  • Process Development – Custom synthesis from kg – metric tons
  • cGMP Small Molecule API Manufacturing (Phase 1, Phase 2, Phase 3, Commerical)
  • cGMP Medical Grade Polymers, Analytical Method Development

Flagship technologies: 

  • Controlled Substances
  • Cryogenic Chemistry -90°C
  • Lyophilization, Small/Large Scale Chromatography
  • Tangential Flow Filtration

Last inspection: July 2018 FDA Inspection

Address ZI de Limay 2, 8 Rue de Rouen
78440 Porcheville
Phone +33 1 34 79 57 00
Market Pharmaceutical, Specialty Ingredients & Cosmetics
Mail ContactSeqensPCV@seqens.com
More information

Surface: 40 000 m²

 

Lab surface: 2 000 m²

 

Capabilities:

  • 4 kilo-labs
  • 2 cGMP pilot plants with 11 multipurpose reactors from 100 L to 2 800 L (total capacity of 12 m³)
  • Temperature range: -15/+150°C  (hastelloy reactor: -80/+200°C)
  • 3 finishing rooms (agitated filter dryers, filters, dryers, milling and sieving equipments)

Flagship technologies:

  • Crystallization expertise and technologiesd(salt, co-crystal and polymorph screenings, process development)
  • Process Safety expertise and tecnologies
  • Flow chemistry for fine chemicals
  • Potent API process development
  • Genotoxic Impurities
  • Issue Management
  • Generic A.P.I Solid state expertis

Last inspection: ANSM  October 2018

Certification: cGMP

 

Number of scientists: 110

 

Other: Ecosystem Pharma with integrated services

 
Address 70 Allée Graham Bell
30000 Nîmes
Phone +33 4 66 70 64 64
Market Pharmaceutical, Specialty Ingredients & Cosmetics
Mail seqensrdnimesinfo@seqens.com
More information

Surface: 1 000 m²

Lab surface: 500 m²

Capacities:

  • 1 kilo-lab in fermentation (80 L total capacity)
  • Robotic platform for highthroughput screening (HTS)
  • Analytical platform for chromatography (GC, GC-MS, U-HPLC)

Flagship technologies: 

  • Protein engineering
  • Microbiology aerobic & anaerobic
  • Syngas fermentation
  • Enzymes & strains fermentation
  • Biochemistry
  • Biocatalysis
  • Design of experiments (DoE)
  • Data mining

Number of scientists: 19

Address 88 Jackson Road, Building 649
MA 01434 Devens
Business Line R&D center
Phone (978) 772 2111
Market Pharmaceutical
Mail Accueil@seqens.com
More information

Lab surface: 1 000 m²

Capabilities:

  • Controlled substances (Schedule II-V)
  • 5 Kilo-Labs

Number of scientists: 30