SEQENS offers a full range of proprietary intermediates (non-regulated, RSM and GMP), from our pre-GMP and GMP plants. We supply  pharma intermediates with a wide range of quantities.​

Using in-house  technologies such as Biocatalysis or Flow chemistry,  Seqens can also  develop non-exclusive  key intermediates for the production of your APIs at customer’s request to support your derisking strategy or new development.​

OUR PORTFOLIO  INTERMEDIATES  INCLUDES:​

  • D-Serine for production of N-BOC D-Serine or Cycloserine for example​
  • Acid chlorides derivatives like Decanoyl chloride, 5-Chlorovaleroyl chloride​
  • Acid & anhydrides like 3-phenyl propionic acid, Benzoic anhydride​
  • Amino derivatives (R)-2-(Aminomethyl)-1-ethylpyrrolidine​
  • Benzofuran derivatives  like (2-Butylbenzofuran-3-yl)(4-hydroxyphenyl)methanone for Amiodarone​
  • Acrolein derivatives like 2-(2-bromoethyl) 1,3 dioxolane ​
  • Phosphonates like : Tetraisopropyl methylene diphosphonate  for Clodronate for example​
  • Quinuclidinone HCL and its derivatives  R-(-)-3-Hydroxyquinuclidine… ​
  • Tartaric acid derivatives for chemical resolutions​
  • Thiophene derivatives like   2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene ​

Our locations

Address Route de Lassay
61410 Couterne
Business Line Lubbricant Additives, Fine Chemicals
Phone +33 2 33 37 50 20
Market Specialty Ingredients
Mail info.AS@seqens.com
More information

Surface: 120, 000 m²

Capabilities: 190 m³ of ISO 9001 reactors and kilo-lab

Flagship technologies: Most standard organic synthesis reactions (large volumes)

Certifications: ISO 9001

Address Raiffeisenstraße 4
77933 Lahr
Business Line Custom Manufacturing, APIs & Intermediates
Phone 49 7821 585 0
Market Pharmaceutical
Mail info-lahr@seqens.com
More information

Surface: 48 000 m²

 

Lab surface: 700 m²

 

Capabilities:

  • Total reactor capacity: 92 m³
  • Reaction vessels: 1 to 6 300 L; temperature  -80°C to +250 °C
  • Multi-purpose state of the art cGMP facilty: 4 independent, vertical integrated production trains 800 L train, 2 x 3 000 L trains plus 1 x 3 000 L low temperature hydrogenation reactor and 6 000 L train
  • Classic two-floor layout Facility: 20 vessels with capacity between 800 and 6 000 L (glaslined and SS)
  • Autoclaves (operational range up to 100 bar)
  • Kilo-Lab: 3 reactors: 25 / 100 / 250 L

Flagship technologies:

  • Hydrogenation
  • Reductive amination
  • Organometallic reactions
  • Protected AADs (Aminoacid derivatives)
  • Carbonylation & Hydroformylation
  • Pressure aminolysis, other reactions under pressure
  • Cryogenic chemistry
  • Enantiopure synthesis
  • Cyanation high volumes (NaCN) C-C coupling
  • Reductions
  • Halogenation

Last inspections:

  • FDA 2018
  • German Pharma Authority 2018

Certifications:

  • GMP
  • ISO 9001
  • ISO 50001

Number of scientists: 25

 
Address 15 Avenue des Frères Lumière
38300 Bourgoin-Jallieu
Business Line Contract Manufacturing & Fine Chemicals
Phone +33 4 74 93 63 33
Market Pharmaceutical
Mail Accueil.bourgoin@seqens.com
More information

Flagship technologies: Distillation